Genetic Characterization of Angiostrongylus Cantonensis Isolates from Different Regions of Ecuador

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Luis Solorzano Alava
Cesar Bedoya Pilozo
Hilda Hernández Alvarez
Misladys Rodriguez
Lazara Rojas Rivero
Francisco Sánchez Amador
Marcelo Muñoz Naranjo
Cecibel Ramirez
Rita Loja Chango
José Pizarro Velastegui
Alessandra Morassuti

Abstract

Angiostrongylus cantonensis (Chen, 1945) was identified in Ecuador for the first time in 2008. Eleven provinces of the country were investigated to establish the phylogenetic relationships between the isolates of the adult parasite and to compare them with those existing in other regions of the world; partial region of subunit 1 of Cytochrome oxidase (COI 1) was amplified, amplicons were sequenced and aligned with the reference sequences of the AC1-AC9 haplotypes. Isolates are grouped in a single clade different from the other previously characterized groups, which represents a novelty for the genetic diversity of the parasite in Latin America and the rest of the world. The parasite has been recently introduced, which has prevented genetic divergence between the isolates.

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Solorzano Alava, L., Bedoya Pilozo , C. ., Hernández Alvarez, H. . . ., Rodriguez , M. ., Rojas Rivero , L. ., Sánchez Amador , F. ., Muñoz Naranjo , M. ., Ramirez , C., Loja Chango , R. ., Pizarro Velastegui , J., & Morassuti , A. . (2021). Genetic Characterization of Angiostrongylus Cantonensis Isolates from Different Regions of Ecuador. INVESTIGATIO, (16), 52–61. https://doi.org/10.31095/investigatio.2021.16.5
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